• Beta cell function after weight loss : a clinical trial comparing gastric bypass surgery and intensive lifestyle intervention 

      Hofsø, Dag; Jenssen, Trond Geir; Bollerslev, Jens; Ueland, Thor; Godang, Kristin; Stumvoll, Michael; Sandbu, Rune; Røislien, Jo; Hjelmesæth, Jøran (Journal article; Tidsskriftartikkel; Peer reviewed, 2011)
      The effects of various weight loss strategies on pancreatic beta cell function remain unclear. We aimed to compare the effect of intensive lifestyle intervention (ILI) and Roux-en-Y gastric bypass surgery (RYGB) on beta cell function. Design One year controlled clinical trial (ClinicalTrials.gov identifier NCT00273104). One hundred and nineteen morbidly obese participants without known diabetes from ...
    • Elevated cholesteryl ester transfer protein activity early in pregnancy predicts prediabetes 5 years later 

      Ueland, Thor; Roland, Marie Cecilie; Michelsen, Annika; Godang, Kristin; Aukrust, Pål; Henriksen, Tore; Bollerslev, Jens; Lekva, Tove (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-29)
      <i>Context</i> - Cholesteryl ester transfer protein (CETP) regulates high-density lipoprotein (HDL) cholesterol levels and interaction between glucose, and HDL metabolism is central in the development of diabetes.<p> <p><i>Objective</i> - We hypothesized that CETP levels would be regulated in diabetic pregnancies. We tested the hypothesis by evaluating CETP activity measured multiple times during ...
    • Evaluation of hypoglycaemia with non-invasive sensors in people with type 1 diabetes and impaired awareness of hypoglycaemia 

      Elvebakk, Ole; Tronstad, Christian; Birkeland, Kåre I.; Jenssen, Trond Geir; Bjørgaas, Marit Ragnhild Rokne; Frøslie, Kathrine Frey; Godang, Kristin; Kalvøy, Håvard; Martinsen, Ørjan Grøttem; Gulseth, Hanne Løvdal (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-10-03)
      People with type 1 diabetes and impaired awareness of hypoglycaemia (IAH) are prone to severe hypoglycaemia. Previous attempts to develop non-invasive hypoglycaemia alarm systems have shown promising results, but it is not known if such alarms can detect severe hypoglycaemia in people with IAH. We aimed to explore whether a combination of non-invasive sensors could reliably evaluate hypoglycaemia ...
    • Hip Structure Analyses in Acromegaly: Decrease of Cortical Bone Thickness After Treatment: A Longitudinal Cohort Study 

      Godang, Kristin; Lekva, Tove; Normann, Kjersti Ringvoll; Olarescu, Nicoleta Cristina; Øystese, Kristin Astrid; Kolnes, Anders Jensen; Ueland, Thor; Bollerslev, Jens; Heck, Ansgar (Journal article; Tidsskriftartikkel; Peer reviewed, 2019-10-03)
      Long‐standing growth hormone (GH) excess causes the skeletal clinical signs of acromegaly with typical changes in bone geometry, including increased cortical bone thickness (CBT). However, a high prevalence and incidence of vertebral fractures has been reported. The aim of this study was to assess the course of cortical bone dimensions in the hip by comparing patients with acromegaly and clinically ...
    • Obesity-related cardiovascular risk factors after weight loss : a clinical trial comparing gastric bypass surgery and intensive lifestyle intervention 

      Hofsø, Dag; Nordstrand, Njord; Johnson, Line Kristin; Karlsen, Tor-Ivar; Hager, Helle; Jenssen, Trond Geir; Bollerslev, Jens; Godang, Kristin; Sandbu, Rune; Røislien, Jo; Hjelmesæth, Jøran (Journal article; Tidsskriftartikkel; Peer reviewed, 2010)
      Objective: Weight reduction improves several obesity-related health conditions. We aimed to compare the effect of bariatric surgery and comprehensive lifestyle intervention on type 2 diabetes and obesityrelated cardiovascular risk factors. Design: One-year controlled clinical trial (ClinicalTrials.gov identifier NCT00273104). Methods: Morbidly obese subjects (19–66 years, mean (S.D.) body mass ...
    • Prediction of gestational diabetes mellitus and pre-diabetes 5 years postpartum using 75 g oral glucose tolerance test at 14-16 Weeks' gestation 

      Lekva, Tove; Godang, Kristin; Michelsen, Annika E.; Qvigstad, Elisabeth; Normann, Kjersti R.; Norwitz, Errol R.; Tore, Henriksen; Bollerslev, Jens; Roland, Marie; Ueland, Thor (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-09-06)
      Early detection and treatment of women at risk for gestational diabetes mellitus (GDM) could improve perinatal and long-term outcomes in GDM women and their offspring. We explored if a 75 g oral glucose tolerance test (OGTT) at 14-16 weeks of gestation could identify women who will (1) develop GDM or give birth to large-for-gestational-age (LGA) babies in 1031 pregnant women from the STORK study ...
    • Visceral fat is strongly associated with post-transplant diabetes mellitus and glucose metabolism 1 year after kidney transplantation 

      Von Düring, Marit Elizabeth; Jenssen, Trond Geir; Bollerslev, Jens; Åsberg, Anders; Godang, Kristin; Hartmann, Anders (Journal article; Tidsskriftartikkel; Peer reviewed, 2016-11-16)
      Body composition after kidney transplantation is linked to glucose metabolism, and impaired glucose metabolism is associated with increased risk of cardiovascular events and death. One year after transplantation we examined 150 patients for new-onset diabetes performing OGTTs and body composition measurements including visceral adipose tissue (VAT) content from dual-energy X-ray absorptiometry ...